To be angry and bored because something unpleasant has been happening for a long time
Annoyed about or bored with (someone or something) and unwilling to put up with them any longer (informal)
Similarly: be sick to death of something/doing something
Examples:
- You're been giving me the same old excuses for months and I was sick and tired of hearing them.
- I am sick and tired of all the criticism
- I've been treated like dirt for two years now and I'm sick to death of it.